The Augusta Cemetery Family Trees

Dr. George Harold MangunAge: 63 years19111975

Name
Dr. George Harold Mangun
Name prefix
Dr.
Given names
George Harold
Surname
Mangun
Birth September 1, 1911 29 31
Birth of a sisterMarjorie Louise Mangun
August 22, 1913 (Age 23 months)
Publication: Ancestry.com - Owner: gmcgowan2
Census January 28, 1920 (Age 8 years)
Citation details: Sheet 10A, SD 14, ED 88
Text:
MABEL MANGUN, Head, Age 39, Married, Born Ohio, Parents born Ohio, Farmer, general, Husband in ____ _____? ALICE MANGUN, Daughter, Age 12, Born Colorado, Parents born Ohio RONALD MANGUN, Son, Age 9, Born Colorado, Parents born Ohio GEORGE MANGUN, Son, Age 8, Born Colorado, Parents born Ohio MARJORIE MANGUN, Daughter, Age 6, Born Colorado, Parents born Ohio
Death of a fatherBenedict Wiley Mangun
February 20, 1920 (Age 8 years)
Cause: Tuberculosis (general); Lungs; Peritoneum; shoulder joints; Contributig: Manic depressive
Citation details: Volume #3218, Certificate #17067
Text:
MANGUN, Death date: 2/20/1920, Stark County Volume #3218, Certificate #17067
Citation details: Cert. #17067
Text:
Name : Ben Manguin Titles : Death date : 20 Feb 1920 Death place : Perry Twp., Stark, Ohio Birth date : Estimated birth year : 1883 Birth place : Oh Age at death : 37 years Gender : Male Marital status : Married Race or color : Caucasian Street address : Occupation : Farmer Residence : Deerfield, Oh Burial date : 23 Feb 1920 Burial place : Augusta, Oh Cemetery name : Augusta, Spouse name : Mabel Manguin Father name : J.W. Manguin Father titles : Father birth place : Mother name : Mother titles : Mother birth place : GSU film number : 1985129 Digital GS number : 4022033 Image number : 2786 Certificate number : fn 17067 Collection : Ohio Deaths 1908-1953
Note:
Informant: Records, State Hospital, Massillon, OH. Undertaker - John Rutledge, Augusta, O.
Burial of a fatherBenedict Wiley Mangun
February 23, 1920 (Age 8 years)
Cemetery: Augusta Cemetery, Section C, Row 10
Publication: Unpublished
Text:
Permit No. 100, Date of Interment 2/23/2930; Cause of death, Tuberculosis; Place of death, Massillon; Undertaker John Rutledge, Augusta.
Publication: Carroll County Genealogical Society, Carrollton, Ohio 44615
Citation details: Page 35
Text:
MANGUN, Benedict W. 1882-1920
Birth of a sisterMary Elizabeth Mangun
April 13, 1920 (Age 8 years)
Citation details: Cert. #41601
Note: Mary Elizabeth Mangun was born 1m 24d after her father's death.
Death of a sisterMary Elizabeth Mangun
July 15, 19215 p.m. (Age 9 years) Age: 1 year 3 months 2 days
Cause: Whooping Cough; Contributory, Bronchitis & Convulsions
Citation details: Cert. #41601
Text:
Name : Mary Elizabeth Mangun Titles : Death date : 15 Jul 1921 Death place : Alliance, Stark, Ohio Birth date : 13 Apr 1920 Estimated birth year : Birth place : Alliance, Ohio Age at death : 1 year 3 months 2 days Gender : Female Marital status : Single Race or color : Caucasian Street address : 631 1/2 S. Linden Ave. Occupation : Residence : Burial date : 17 Jul 1921 Burial place : Augusta, Ohio Cemetery name : Spouse name : Father name : B. W. Mangun Father titles : Father birth place : Delroy, Ohio Mother name : Mable Gause Mother titles : Mother birth place : Deerfield, Ohio GSU film number : 1991689 Digital GS number : 4022227 Image number : 399 Certificate number : fn 41606 Collection : Ohio Deaths 1908-1953
Note:
Informant: Mable Mangun Undertaker: W. E. Wood, Atwater, OH
Burial of a sisterMary Elizabeth Mangun
July 17, 1921 (Age 9 years)
Citation details: Cert. #41601
Note: Mary Elizabeth is buried in an unmarked Grave. It is assumed she is buried with her father and grandparents in Section C, Row 10.
Death of a maternal grandmotherMary Reed
January 29, 1922 (Age 10 years)
Citation details: Certificate number: fn 5449
Text:
Name: Mary Reed Gause Titles: Death date: 29 Jan 1922 Death place: Alliance, Stark, Ohio Birth date: 06 Sep 1852 Estimated birth year: Birth place: Deerfield, Ohio Age at death: 69 years 4 months 22 days Cause of death: Bronchial Pneumonia Gender: Female Marital status: Widowed Race or color: Caucasian Street address: 815 S. Linden Street, 3rd Ward Occupation: Housewife Residence: 815 S. Linden St., 3rd Ward Burial date: 31 Jan 1922 Burial place: Atwater, Ohio Cemetery name: Spouse name: Geo. Gause Father name: Anthony Ried Father titles: Father birth place: Lisbon, Ohio Mother name: Elizabeth La... Mother titles: Mother birth place: Deerfield, Ohio Informant: Mrs. Mable Mangun, Alliance, Ohio GSU film number: 1991863 Digital GS number: 4022270 Image number: 2869 Reference number: fn 5449 Collection: Ohio Deaths 1908-1953
Burial of a maternal grandmotherMary Reed
January 31, 1922 (Age 10 years)
Citation details: Certificate number: fn 5449
Census April 2, 1930 (Age 18 years)
Citation details: Sheet 1A, SD 10, ED 34-45
Text:
ROSIE UHL, Head, Owns home - value 2500, Age 68, Widowed, First married at age 27, Born Germany, Parents born Germany, Farmer, General Farming GEO W. MANGUN, Lodger, Age 18, Single, Born Colorado, Parents born Ohio
Death of a paternal grandfatherJames Wiley Mangun
November 25, 1936 (Age 25 years) Age: 86
Cause: Pneumonia, Bronchitis
Citation details: Certificate #67379
Text:
Name : James W. Mangun Titles : Death date : 25 Nov 1936 Death place : Augusta, Carroll, Ohio Birth date : 02 Mar 1850 Estimated birth year : Birth place : Carroll Co. Age at death : 86 years Gender : Male Marital status : Married Race or color : Caucasian Street address : Occupation : Farmer Residence : Burial date : 27 Nov 1936 Burial place : Augusta Cemetery name : Spouse name : Ollie Mangun Father name : Benedist Mangun Father titles : Father birth place : Carroll Co. Mother name : Mother titles : Mother birth place : GSU film number : 2022732 Digital GS number : 4057795 Image number : 312 Certificate number : fn 67379 Collection : Ohio Deaths 1908-1953
Note:
Informant: Ollie Mangun Undertaker: Rutledge Jackson, Minerva, OH
Burial of a paternal grandfatherJames Wiley Mangun
November 27, 1936 (Age 25 years)
Cemetery: Augusta Cemetery, Section C, Row 10
Publication: Unpublished
Text:
Permit No. 73, Date of Interment, Nov 27, 1936, Name of Deceased, James W. Mangun, age 86, Cause of death, Pneumonia, Bronchitis, Place of Death, Augusta Tp, Undertaker, Rutledge Jackson, Minerva.
Publication: Carroll County Genealogical Society, Carrollton, Ohio 44615
Citation details: Page 35
Text:
MANGUN James Wiley 1850-1936 Lydia Olive 1860-1939
Education
Ph.D. in Chemistry
1938 (Age 26 years)
Death of a paternal grandmotherLydia Olive Daniel
March 30, 19396 p.m (Age 27 years) Age: 79
Cause: Hypertension; Cardiac decomposition
Citation details: Certificate #21384
Text:
MANGUN, Olive Death date: 3/30/1939, Carroll County Certificate #21384
Citation details: Cert. #21384
Text:
Name : Olive Mangun Titles : Death date : 30 Mar 1939 Death place : Augusta, Carroll, Ohio Birth date : 23 May 1860 Estimated birth year : Birth place : Carroll Co Age at death : 79 years Gender : Female Marital status : Widowed Race or color : Caucasian Street address : Occupation : Housewife Residence : Burial date : 01 Apr 1939 Burial place : Augusta Cemetery name : Spouse name : James Mangun Father name : James Daniel Father titles : Father birth place : Carroll Co, Oh Mother name : Louisa Deford Mother titles : Mother birth place : Carroll Co, Oh GSU film number : 2023711 Digital GS number : 4027219 Image number : 439 Certificate number : fn 21384 Collection : Ohio Deaths 1908-1953
Note:
Informant: Howard Mangun Undertaker: Rutledge Jackson, Minerva, OH
Burial of a paternal grandmotherLydia Olive Daniel
April 1, 1939 (Age 27 years)
Cemetery: Augusta Cemetery, Section C, Row 10
Publication: Carroll County Genealogical Society, Carrollton, Ohio 44615
Citation details: Page 35
Text:
MANGUN James Wiley 1850-1936 Lydia Olive 1860-1939
Military
Major, U.S. Army, World War II
about 1942 (Age 30 years)

Death of a motherMabel C. Gause
June 19, 1944 (Age 32 years) Age: 64
Cause: Myocarditis
Citation details: Certificate #40764
Text:
MANGUN, Mable Death date: 6/19/1944, Stark County Certificate #40764
Citation details: Cert. #40764
Text:
Name : Mable Mangun Titles : Death date : 19 Jun 1944 Death place : Alliance, Stark, Ohio Birth date : 02 Mar 1880 Estimated birth year : Birth place : Deerfield, Ohio Age at death : 64 years 3 months 12 days Gender : Female Marital status : Widowed Race or color : Caucasian Street address : 936 1/2 South Linden Occupation : Housewife Residence : Alliance, Stark, Ohio Burial date : 22 Jun 1944 Burial place : Augusta Cemetery name : Spouse name : Ben Father name : George Gause Father titles : Father birth place : Bunker Hill, Ohio Mother name : Mary Reed Mother titles : Mother birth place : Deerfield, O GSU film number : 2032362 Digital GS number : 4122092 Image number : 1659 Certificate number : fn 40764 Collection : Ohio Deaths 1908-1953
Burial of a motherMabel C. Gause
June 22, 1944 (Age 32 years)
Publication: Unpublished
Text:
Permit 208, Date of Interment June 22, 1944, Name of Deceased, Mabel Mangun, age 64, Cause of death Myocarditis; Place of death Alliance, O; Undertaker, Myers Funeral Home, Alliance, O.
Residence August 1952 (Age 40 years)
Publication: Ancestry.com. New York Passenger Lists, 1820-1957 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2006.
Citation details: Year: 1952; Microfilm serial: T715; Microfilm roll: T715_8203; Line: 7; .
Text:
15713 Heyden Ave. Detroit, 23, Michigan
Travel
s. s. Maasdam
August 11, 1952 (Age 40 years)
Publication: Ancestry.com. Border Crossings: From Canada to U.S., 1895-1956 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2008.
Citation details: List No. 21
Text:
Name: George H Mangun Marital Status: Married Destination in U.S.: 15713 Heyden Ave., Detroit, Mich. Arrival Date: 19 Aug 1952 Birthplace: Montrose, Colorado Birth Country: USA Gender: Male U.S. Passport No. 691715 Name: Ruth R Mangun Marital Status: Married Destination in U.S.: 15713 Heyden Ave., Detroit, Mich. Arrival Date: 19 Aug 1952 Birthplace: Kearney, Nebraska Birth Country: USA Gender: Female U.S. Passport No. 691715 Ship Name: s. s. Maasdam Port of Arrival: Montreal, Quebec, Canada Date of Arrival: Aug. 19th, 1952 Port of Departure: Rotterdam, Netherlands Date of Departure: Aug. 11th, 1952
Travel
Queen Elizabeth
August 28, 1952 (Age 40 years)
Publication: Ancestry.com. New York Passenger Lists, 1820-1957 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2006.
Citation details: Year: 1952; Microfilm serial: T715; Microfilm roll: T715_8203; Line: 7; .
Text:
Name: George Mangun Arrival Date: 2 Sep 1952 Estimated Birth Year: abt 1912 Age: 40 Gender: Male Marital Status: Married Address: 15713 Heyden, Detroit, 23, Michigan Port of Departure: Southampton, England Ship Name: Queen Elizabeth Port of Arrival: New York, New York - Did not embark Nativity: Colorado Line: 7 Microfilm Serial: T715 Microfilm Roll: T715_8203 Birth Location: Colorado Page Number: 123
Occupation
Director of Research, Warner-Chilcott Laboratories
1953 (Age 41 years)
Travel
Flight No. SE-BDP (Swedish) SK911 from Copenhagen/Denmark to New York
August 16, 1955 (Age 43 years)

Publication: Ancestry.com. New York Passenger Lists, 1820-1957 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2006.
Citation details: Year: 1955; Microfilm serial: T715; Microfilm roll: T715_8622; Line: 13; .
Text:
Name: George H Mangun Arrival Date: 17 Aug 1955 Port of Departure: Copenhagen, Denmark Port of Arrival: New York, New York Line: 13 Microfilm Serial: T715 Microfilm Roll: T715_8622 Page Number: 401
Accomplishments
Developed a Drug that Helps Reduce the Loss of Life from Premature Labor
July 1956 (Age 44 years)

Citation details: The Billings (Montana) Gazette - July 10, 1956
Text:
The hormone is Relaxin, a natural sex hormone playing a vital role in the birth process. Warner-Chilcott Laboratories of New York announced success in making supplies available for the first time, under the name Releasin, to help reduce the lossof life from premature labor. In some cases when the hormone halted the labor, the normal delivery later on was quick and nearly painless, said Dr. George H. Mangun, director of research of the laboratories. See NOTES for complete text.
Travel
Montana
July 1957 (Age 45 years)

Citation details: (Butte) Montana Standard - Thursday, July 11, 1957
Text:
Dr. George Mangun, since 1952 director of research for Warner-Chilcott, producer of pharmaceutical supplies, recently returned to Montana in different fashion than the first time he came to the state in 1928. See NOTES for complete text.
Residence June 1960 (Age 48 years)
Citation details: Bridgeport (Connecticut) Sunday Post - June 5, 1960
Text:
MENDHAM, N.J. -- (AP) If a surprisingly large number of the nation's crack biologists hail from this vicinity a couple of decades hence, it will mean that Dr. George H. Mangun has had his benign revenge on his neighbors. See NOTES for complete text.
Residence August 1960 (Age 48 years)
Citation details: Sunday Gazette-Mail (Charleston, WV) - August 7, 1960
Text:
BROOKSIDE, N.J. -- (AP) -- Dr. George H. Mangun, who gave away 3,000 mice when his garage-laboratory was closed by local officials, is on his way to Tempe, Ariz.
Death of a sisterAlice C. Mangun
October 15, 1973 (Age 62 years)
Citation details: Certificate: 082053; Volume: 21475
Text:
Name: Alice C Herron Birth Date: Est. 1907 Gender: Female Race: White Residence County: Trumbull Residence State: Ohio Residence Country: United States Death Date: 15 Oct 1973 Hospital of Death: Forum Health Trumbull Memorial City of Death: Warren County of Death: Trumbull Certificate: 082053 Age at Death: 66 Certifier: Physician Autopsy: No autopsy Marital Status: Widowed
Citation details: Number: 345-16-9441;Issue State: Illinois;Issue Date: Before 1951.
Text:
Name: Alice Herron SSN: 345-16-9441 Last Residence: 44481 Warren, Trumbull, Ohio, United States of America Born: 2 Aug 1907 Died: Oct 1973 State (Year) SSN issued: Illinois (Before 1951 )
Death July 6, 1975 (Age 63 years)
Text:
George MANGON Birth Date: 1 Sep 1911 Death Date: Jul 1975 Social Security Number: 288-14-3604 State or Territory Where Number Was Issued: Ohio Death Residence Localities ZIP Code: 85001 Localities: Phoenix, Maricopa, Arizona
Text:
Name: George H Mangun Birth Date: Est. 1912 Gender: Male Race: White Death Date: 6 Jul 1975 Hospital of Death: Alliance City Hospital City of Death: Alliance County of Death: Stark Certificate: 054017 Age at Death: 63 Certifier: Physician Marital Status: Married
Burial after July 6, 1975
Publication: Unpublished
Text:
Permit 4577, Date of DEATH, July 6, 1975; Name of deceased, Dr. George H. Mangun, age 63; Cause of death, Provisional; Place of death, Alliance, OH, Undertaker, Edgar H. Turkle, Jr., Alliance, O.
Family with parents - View this family
father
mother
Marriage: August 29, 1906
11 months
elder sister
Alice C. Mangun
Birth: August 2, 1907 25 27Colorado
Death: October 15, 1973Forum Health Trumbull Memorial, Warren, Trumbull, Ohio
15 months
elder brother
15 months
elder brother
19 months
himself
2 years
younger sister
7 years
younger sister
Mary Elizabeth Mangun
Birth: April 13, 1920 37 40Alliance, Stark, OH
Death: July 15, 1921631-1/2 S Linden Ave, Alliance, Stark, OH
Family with Private - View this family
himself
wife
Private
Family with Elizabeth Krasnonis - View this family
himself
wife
son
Private
daughter
Private
son
Private

BirthUS Social Security Death Index
BirthTombstone - Augusta Cemetery
CensusCensus, Federal, 1920
Citation details: Sheet 10A, SD 14, ED 88
Text:
MABEL MANGUN, Head, Age 39, Married, Born Ohio, Parents born Ohio, Farmer, general, Husband in ____ _____? ALICE MANGUN, Daughter, Age 12, Born Colorado, Parents born Ohio RONALD MANGUN, Son, Age 9, Born Colorado, Parents born Ohio GEORGE MANGUN, Son, Age 8, Born Colorado, Parents born Ohio MARJORIE MANGUN, Daughter, Age 6, Born Colorado, Parents born Ohio
CensusCensus, Federal, 1930
Citation details: Sheet 1A, SD 10, ED 34-45
Text:
ROSIE UHL, Head, Owns home - value 2500, Age 68, Widowed, First married at age 27, Born Germany, Parents born Germany, Farmer, General Farming GEO W. MANGUN, Lodger, Age 18, Single, Born Colorado, Parents born Ohio
MilitaryTombstone - Augusta Cemetery
ResidenceNew York Passenger Lists, 1820-1957
Publication: Ancestry.com. New York Passenger Lists, 1820-1957 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2006.
Citation details: Year: 1952; Microfilm serial: T715; Microfilm roll: T715_8203; Line: 7; .
Text:
15713 Heyden Ave. Detroit, 23, Michigan
TravelBorder Crossings: From Canada to U.S., 1895-1956
Publication: Ancestry.com. Border Crossings: From Canada to U.S., 1895-1956 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2008.
Citation details: List No. 21
Text:
Name: George H Mangun Marital Status: Married Destination in U.S.: 15713 Heyden Ave., Detroit, Mich. Arrival Date: 19 Aug 1952 Birthplace: Montrose, Colorado Birth Country: USA Gender: Male U.S. Passport No. 691715 Name: Ruth R Mangun Marital Status: Married Destination in U.S.: 15713 Heyden Ave., Detroit, Mich. Arrival Date: 19 Aug 1952 Birthplace: Kearney, Nebraska Birth Country: USA Gender: Female U.S. Passport No. 691715 Ship Name: s. s. Maasdam Port of Arrival: Montreal, Quebec, Canada Date of Arrival: Aug. 19th, 1952 Port of Departure: Rotterdam, Netherlands Date of Departure: Aug. 11th, 1952
TravelNew York Passenger Lists, 1820-1957
Publication: Ancestry.com. New York Passenger Lists, 1820-1957 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2006.
Citation details: Year: 1952; Microfilm serial: T715; Microfilm roll: T715_8203; Line: 7; .
Text:
Name: George Mangun Arrival Date: 2 Sep 1952 Estimated Birth Year: abt 1912 Age: 40 Gender: Male Marital Status: Married Address: 15713 Heyden, Detroit, 23, Michigan Port of Departure: Southampton, England Ship Name: Queen Elizabeth Port of Arrival: New York, New York - Did not embark Nativity: Colorado Line: 7 Microfilm Serial: T715 Microfilm Roll: T715_8203 Birth Location: Colorado Page Number: 123
TravelNew York Passenger Lists, 1820-1957
Publication: Ancestry.com. New York Passenger Lists, 1820-1957 [database on-line]. Provo, UT, USA: The Generations Network, Inc., 2006.
Citation details: Year: 1955; Microfilm serial: T715; Microfilm roll: T715_8622; Line: 13; .
Text:
Name: George H Mangun Arrival Date: 17 Aug 1955 Port of Departure: Copenhagen, Denmark Port of Arrival: New York, New York Line: 13 Microfilm Serial: T715 Microfilm Roll: T715_8622 Page Number: 401
AccomplishmentsNewspaper Article
Citation details: The Billings (Montana) Gazette - July 10, 1956
Text:
The hormone is Relaxin, a natural sex hormone playing a vital role in the birth process. Warner-Chilcott Laboratories of New York announced success in making supplies available for the first time, under the name Releasin, to help reduce the lossof life from premature labor. In some cases when the hormone halted the labor, the normal delivery later on was quick and nearly painless, said Dr. George H. Mangun, director of research of the laboratories. See NOTES for complete text.
TravelNewspaper Article
Citation details: (Butte) Montana Standard - Thursday, July 11, 1957
Text:
Dr. George Mangun, since 1952 director of research for Warner-Chilcott, producer of pharmaceutical supplies, recently returned to Montana in different fashion than the first time he came to the state in 1928. See NOTES for complete text.
ResidenceNewspaper Article
Citation details: Bridgeport (Connecticut) Sunday Post - June 5, 1960
Text:
MENDHAM, N.J. -- (AP) If a surprisingly large number of the nation's crack biologists hail from this vicinity a couple of decades hence, it will mean that Dr. George H. Mangun has had his benign revenge on his neighbors. See NOTES for complete text.
ResidenceNewspaper Article
Citation details: Sunday Gazette-Mail (Charleston, WV) - August 7, 1960
Text:
BROOKSIDE, N.J. -- (AP) -- Dr. George H. Mangun, who gave away 3,000 mice when his garage-laboratory was closed by local officials, is on his way to Tempe, Ariz.
DeathUS Social Security Death Index
Text:
George MANGON Birth Date: 1 Sep 1911 Death Date: Jul 1975 Social Security Number: 288-14-3604 State or Territory Where Number Was Issued: Ohio Death Residence Localities ZIP Code: 85001 Localities: Phoenix, Maricopa, Arizona
DeathOhio Dept of Health, Ohio Death Index, 1958-2000, database on line, Provo, UT
Text:
Name: George H Mangun Birth Date: Est. 1912 Gender: Male Race: White Death Date: 6 Jul 1975 Hospital of Death: Alliance City Hospital City of Death: Alliance County of Death: Stark Certificate: 054017 Age at Death: 63 Certifier: Physician Marital Status: Married
BurialAugusta Cemetery Burial Records
Publication: Unpublished
Text:
Permit 4577, Date of DEATH, July 6, 1975; Name of deceased, Dr. George H. Mangun, age 63; Cause of death, Provisional; Place of death, Alliance, OH, Undertaker, Edgar H. Turkle, Jr., Alliance, O.
NoteNewspaper Article
Citation details: The Billings (Montana) Gazette - July 10, 1956
NoteNewspaper Article
Citation details: (Butte) Montana Standard - Thursday, July 11, 1957
NoteNewspaper Article
Citation details: Bridgeport (Connecticut) Sunday Post - June 5, 1960
NoteNewspaper Article
Citation details: Sunday Gazette-Mail (Charleston, WV) - August 7, 1960
Note
The Billings Gazette Billings, Montana Tuesday Morning, July 10, 1956 New Female Sex Hormone Aids In Saving Premature Babies NEW YORK (AP) -- A new female sex hormone promises to save thousands of babies who now are born prematurely, a drug firm said Monday. It can work in either of two ways to save babies who are born too soon from premature labor. It sometimes stops the premature labor contractions, thus giving the infant more time to develop in the womb. Or it can make the premature birth easier so the babies are not fatally injured before being born. The hormone is Relaxin, a natural sex hormone playing a vital role in the birth process. Warner-Chilcott Laboratories of New York announced success in making supplies available for the first time, under the name Releasin, to help reduce the lossof life from premature labor. In normal pregnancy, Relaxin stretches pelvic ligaments and softens tissues of the womb and birth canal at the time of delivery. It also makes labor contractions less severe. Lack of Relaxin is believed responsible for premature labor andstillbirths. In many cases of premature labor, there are strong contractions but the birth canal is not ready and the baby is fatally injured. In some cases when the hormone halted the labor, the normal delivery later on was quick and nearly painless, said Dr. George H. Mangun, director of research of the laboratories. In clinical trials, Relaxin was credited with saving seven out of 10 babies who otherwise probably would have been stillborn. The hormone drug is still scarce, and expensive. Costs of treating one case in a hospital are estimated at from $150 to $175. Some 200,000 babies are stillborn each year from premature labor. At present there will be enough Relaxin to treat only some 18,000 women annually, but this could mean saving 12,000 to 14,000 infants, Dr. Mangun said. The hormone is obtained from the ovaries of pregnant sows, involving elaborate work to separate out purified Relaxin. From 500 sows, only enough is obtained to treat 6 to 8 women. More efficient sources of supply are being sought. The hormone appears most effective when given to women threatened with premature labor in the 29th to 32nd weeks or pregnancy. In time, when supplies increase, it might be used to induce delivery at desired times, and possibly make birth easier.
Note
Montana Standard Butte, Montana Thursday, July 11, 1957 Research Director Returns to State BOZEMAN (UP) -- Dr. George Mangun, since 1952 director of research for Warner-Chilcott, producer of pharmaceutical supplies, recently returned to Montana in different fashion than the first time he came to the state in 1928. Mangun, then 17, rode a freight train to Livingston where Lloyd and Mary Shellhamer, now of Bozeman, gave him work on their ranch. He attended Clyde Park High School. A state physics contest scholarship led to his enrolling at Montana StateCollege. After he was graduated from MSC, Mangun received a doctorate at Western Reserve University, Cleveland, where he taught for several years. Later, he taught at the Medical College of South Carolina at Charleston, served as associate director of the University of Chicago Toxicity Laboratory and was director of clinical chemistry at Henry Ford General Hospital, Detroit. Research under his direction has included development of the hormone, releasin, and a new tranquilizer known as pacatal. Mangun says, "chemistry, supported by physics, is undoubtedly a backbone to progress in many fields, especially biology, agriculture and medicine. I would by all means urge that MSC continue its policy to train young people in these basicscientific subjects."
Note
Bridgeport Sunday Post Bridgeport, Connecticut June 5, 1960 Anyone Want a Mouse or Two? Biochemist Hands Them Out By Tom Henshaw MENDHAM, N.J. -- (AP) If a surprisingly large number of the nation's crack biologists hail from this vicinity a couple of decades hence, it will mean that Dr. George H. Mangun has had his benign revenge on his neighbors. Dr. Mangun, a 48-year-old biochemist, is moving West -- and taking his experimental research with him, much to the official relief of several squeamish neighbors -- but he'll be leaving a scientific legacy behind him. The legacy: a colony of 3,000 little white mice which the doctor has been passing out by the fistful to any youngster who goes to his barnyard laboratory and asks for them. Loses Zoning Battle "It was the kids' idea, really," grins Dr. Mangun, who fought a losing battle for a year and a half against a zoning ordinance interpretation that, in effect, bans large-scale mouse-breeding from the rural confines of Washington valley nearMorristown. "At first I thought of driving my trail herd through the center of town on my way West," he says, chuckling. "But then the neighborhood kids started calling up to ask if they could have a mouse. "I decided then and there that my revenge for this town would be to make biologists out of all the children so they will amount to more than this generation." Surprisingly, most of the youngsters told Dr. Mangun they wanted the mice for serious study purposes, rather than pets. A number went to Rutger students for home studies, mostly in genetics. And many went to fledgling scientists in younger agebrackets. Seventh Grade Project Jerry Valorant and Kevin Bennett, both 13, picked up several to use in a special project for the seventh grade of the Mendham township school. "I feed mine nourishing food, " says Kevin. "And I feed mine food that is not nourishing," adds Jerry. "Mine are healthy," says Kevin. "Mine are sick," adds Jerry. "When we get through we're going to write a report for our science teacher." Dr. Mangun's experiments, which he has been conducting independently under a $15,000 a year grant from a pharmaceutical firm, are a bit more complicated than that. They deal with basic research into the mysteries of enzymes and pain killingagents. The laboratory and mouse colony, set up two years ago in a remodeled barn, drew complaints almost immediately from a "next door" neighbor who lives about 300 yards away down a dirt road. The complaint: Dr. Mangun was conducting a business in aresidential zone. Town fathers agreed. Has to Move Troupe Now, Dr. Mangun is negotiating to move his experiments -- and his wife, three small children, three dogs, two Nubian goats and a cat -- to Arizona State college at Tempe, where he'll teach as well as experiment. Neighborhood youngsters will miss him and his mice. A number of kids have served as junior assistants in the Mangun lab, sweeping up, feeding and watering the mice and listening to the doctor's informal lectures on the care and breeding of mice. How have the parents of Mendham -- and places as far away as Teaneck -- taken to the mass dispersal of white mice? "They've kind of liked the idea of the kids experimenting at home," says Dr. Mangun. "I've been giving away a few at a time for some years and I've never had a complaint. No returns, either. "In fact, one parent even dropped around to tell me he liked the idea because it was teaching his son the facts of life and saving him a lot of trouble. "Another youngster went home and told his folks he had learned why a man was worth more than a woman. He figured that out because you can mate five female mice to one male. "Right or wrong, Dad got a new standing in that household."
Note
Sunday Gazette-Mail Charleston, West Virginia August 7, 1960 Biochemist Who Lost Mice Is Going West BROOKSIDE, N.J. -- (AP) -- Dr. George H. Mangun, who gave away 3,000 mice when his garage-laboratory was closed by local officials, is on his way to Tempe, Ariz. Mangun, a biochemist, left with his family Friday for a teaching and research job at Arizona State College. He had been experimenting on pain-killing drugs here when Mendham Township ruled that his research violated zoning laws. Mangun then distributed his mice among neighborhood children. His wife, Libby, and their children, Ronnie, 4, Debbie, 2, and Lloyd, 7 months, were sorry to leave friends. But Mangun looked forward to his new research position. "They encourage progress in Arizona, not hinder it," he said.